Biocan novel DHPPI, Lyophilisate and solvent for suspension for injection for dogs
Canine live vaccine against parvovirosis, distemper, inf. hepatitis, inf. laryngotracheitis and parainfluenza.
Composition per 1 ml dose:
Lyophilisate (live attenuated):
Canine Distemper virus, strain CDV Bio 11/A - min. 103.1 TCID50*, max. 105.1 TCID50*
Canine Adenovirus Type 2, strain CAV-2 Bio 13 - min. 103.6 TCID50*, max. 105.3 TCID50*
Canine Parvovirus Type 2b, strain CPV-2b Bio 12/B - min. 104.3 TCID50* , max. 106.6 TCID50*
Canine Parainfluenza Type 2 virus, strain CPiV-2 Bio 15 - 103.1 TCID50*, max. 105.1 TCID50*
* Tissue culture infectious dose – 50%
Pharmaceutical form:
Lyophilisate and solvent for suspension for injection.
Lyophilisate: Spongy matter, white colour. Solvent: Clear colourless liquid.
Target species:
Dogs
Indications for use, specifying the target species:
Active immunization of dogs from 6 weeks of age.
- to prevent mortality and clinical signs caused by canine distemper virus
- to prevent mortality and clinical signs caused by canine adenovirus type 1
- to prevent clinical signs and reduce viral excretion caused by canine adenovirus type 2
- to prevent clinical signs, leukopenia and viral excretion caused by canine
- to prevent clinical signs (nasal and ocular discharge) and reduce viral excretion caused by canine parainfluenza virus
Onset of immunity:
- 3 weeks after the first vaccination for CDV, CAV, CPV,
- 3 weeks after completion of the primary course for CPiV
Duration of immunity:
At least three years following the primary vaccination course for canine distemper virus, canine adenovirus type 1, canine adenovirus type 2 and canine parvovirus. At least one year following the primary vaccination course for canine parainfluenza virus.
The duration of immunity against CAV-2 was not established by challenge. It was shown that 3 years after the vaccination CAV-2 antibodies are still present. Protective immune response against CAV-2 associated respiratory disease is considered to last at least 3 years.
Bioveta